This talk will end with an outline of the COSI team’s plans for a change in its governance structure, leading to more involvement of all members and restructuring of the COSI team. The event is hosted by Andreas Dräger, Bhanwar Lal Puniya, and Juilee Thakar. Bhanwar Lal Puniya will close the event by awarding this year’s poster prizes. This year’s meeting comprises three sessions covering various topics, beginning with “Methods for Modeling and their Applications,” followed by “Modeling Signal Transduction, Gene Regulation, and Protein-Protein Interactions.” It concludes with a session on “Applications of Single Cell Technology.” Two outstanding keynote speakers will present their visions on developments in these fields: Reinhard Laubenbacher from the University of Florida Health and Ana Conesa from the Politechnical University of Valencia, Spain. This brief talk introduces all speakers, organizers, and the main topics of the 2022 meeting. The community of particular interest (COSI) in systems modeling (SysMod) organizes annual gatherings.

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